variola

Definition: (noun) An acute, highly infectious, often fatal disease caused by a poxvirus and characterized by high fever and aches with subsequent widespread eruption of pimples that blister, produce pus, and form pockmarks.

Synonyms: smallpox.

Usage: We could tell from the scars on the faces of the villagers that a variola epidemic had passed through the area in their lifetimes.
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